Help people with airway obstructive diseases breathe easily

and prevent progressive lung damage & respiratory failure

Cila Therapeutics

A clinic-ready stage, biotechnology company developing new inhaled therapies for the treatment of a rare genetic disorder, Primary Ciliary Dyskinesia (PCD), and other respiratory diseases.

"To date, no pharmacological intervention has been approved for Primary Ciliary Dyskinesia (PCD) indication" 

Source:

What is Primary Ciliary Dyskinesia (PCD)?

PCD is a rare disease caused by multiple genetic mutations involving fingerlike projections on airway cells known as "Cilia". It is estimated to affect ~1/10000 birth in the US.

Normal mucus traps pathogens and Cilia move to clear it. In PCD patients, due to genetic reasons, Cilia are dysfunctional so mucus builds up and forms "mucus plugs". These plugs clog airways and initiate a vicious cycle of recurrent infection, airway damage, permanent lung damage, and progression to bronchiectasis.

Symptoms

Patients experience chronic cough, respiratory problems, and recurrent ear and lung infections from birth onwards. A significant number of PCD cases experience life-threatening respiratory failure and some require lung transplantation. Exacerbation of respiratory distress leads to frequent ER visits, hospitalization, poor quality of life for patients, and a huge economic burden on families and the healthcare system. 

Our pipeline

CILA has a robust early-stage pipeline 

COMPOUND

DISCOVERY

INDICATION

PRECLINICAL

PHASE I

PHASE II

PHASE III

Patients resources

FOUNDATIONS FOR OBSTRUCTIVE AIRWAYS DISEASES

ADDITIONAL RESOURCES

LINKS

CONTACT

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SOCIAL